Pharmaceutical intervention on peripheral vascular access in a general acute hospital

Authors

  • Javier Araujo Hospital Hospital Interzonal General de Agudos “Evita”
  • Belén Billordo Hospital Hospital Interzonal General de Agudos “Evita”
  • Camila Alvarez Hospital Hospital Interzonal General de Agudos “Evita”
  • Vanesa Osardo Hospital Hospital Interzonal General de Agudos “Evita”
  • Eugenia Di Líbero Hospital Hospital Interzonal General de Agudos “Evita”

Keywords:

Peripheral intravenous catheter, Clinical pharmacy, Pharmaceutical intervention, Drug related problems

Abstract

Introduction: It is estimated that up to 80% of hospitalized patients require a peripheral intravenous catheter (PIC). Their placement and permanence is related to infectious and non-infectious complications, and to an increase in hospital stay and associated costs. In our hospital, we perform pharmacotherapeutic follow-up of hospitalized patients and our goal is to optimize the prescriptions, among them, the unnecessary use of parenteral therapy and the medical products that it implies.

Objective: To quantify the pharmaceutical interventions (PI) over the removal of PICs in hospitalized patients under pharmacotherapeutic follow-up, to discriminate whether this intervention was carried out as a consequence of other PI and describing the pharmacological groups involved with them.

Materials and methods: An observational and retrospective trial including hospitalized patients. From the pharmacotherapeutic follow-up forms used for data recording, we selected those with the coded intervention "without clinical rationale" (WCR) related to PICs, also recording whether the PI was given simultaneously with "incorrect route of administration" (IRA), or with "end of treatment" (EOT), over drugs that were being administered intravenously.

Results: There were 2783 patients included. The “WCR” PI on PICs was performed in 512 of the total patients under follow-up, resulting in a PIC withdrawal rate of 18.4%. This withdrawal occurred over a PIC that was not being used for drug administration in 22.7% of the cases and related to the PIs “IRA” or “EOT” in the remaining 77.3%. When the withdrawal of PIC was accompanied by the withdrawal of a drug, these were distributed according to: antimicrobials 40.2%, fluid therapy 36.1%, corticosteroids 16.2%, with the remaining distributed among other pharmacological groups.

Conclusions: PIC withdrawal was run by clinical pharmacists in 18.4% of patients under pharmacotherapeutic follow-up; 77.3% of these withdrawals were associated with the PIs “IRA” or “EOT”, in the majority of the cases, over an antimicrobial drug.

References

Keogh S, Mathew S. Peripheral intravenous catheters: A review of guidelines and research. Sydney: ACSQHC; 2019

Marsh N, Webster J, Ullman AJ, Mihala G, Cooke M, Chopra V, Rickard CM. Peripheral intravenous catheter non-infectious complications in adults: A systematic review and meta-analysis. J Adv Nurs. 2020 Dec;76(12):3346-3362

Zhang L, Cao S, Marsh N, Ray-Barruel G, Flynn J, Larsen E, Rickard CM. Infection risks associated with peripheral vascular catheters. J Infect Prev. 2016 Sep;17(5):207-213

Cooke M, Ullman AJ, Ray-Barruel G, Wallis M, Corley A, Rickard CM. Not "just" an intravenous line: Consumer perspectives on peripheral intravenous cannulation (PIVC). An international cross-sectional survey of 25 countries. PLoS One. 2018 Feb 28;13(2):e0193436.

O'Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J, Heard SO, Lipsett PA, Masur H, Mermel LA, Pearson ML, Raad II, Randolph AG, Rupp ME, Saint S; Healthcare Infection Control Practices Advisory Committee (HICPAC). Guidelines for the prevention of intravascular catheter-related infections. Clin Infect Dis. 2011 May;52(9):e162-93.

Grupo de trabajo de la Guía de Práctica Clínica sobre Terapia Intravenosa con Dispositivos no Permanentes en Adultos. Guía de Práctica Clínica sobre Terapia Intravenosa con Dispositivos no Permanentes en Adultos. Ministerio de Sanidad, Servicios Sociales e Igualdad. Agencia de Evaluación de Tecnologías Sanitarias de Andalucía (AETSA); 2014. Guías de Práctica Clínica en el SNS.

Buisson M, Leguelinel G, Bastide S, Beregi JP, Kinowski JM, Frandon J, Chasseigne V. A new clinical approach to improve the appropriate use of peripherally inserted central catheters: a prospective study. Eur J Hosp Pharm. 2021 Nov;28(Suppl 2):e134-e139.

Chasseigne V, Buisson M, Serrand C, Leguelinel-Blache G, Kinowski JM, Goupil J, Beregi JP, Frandon J. Pharmaceutical Analysis of Peripherally Inserted Central Catheter Requests Increases the Use of Single-Lumen Catheters: A Prospective Pilot Study. J Patient Saf. 2022 Jul 11.

Colldén H, Teimori K, Asadian R. Blandbarhet av intravenösa läkemedel behöver uppmärksammas - Kateterocklusion, terapisvikt och embolier kan förebyggas [Compatibility of intravenous medications needs attention. Catheter occlusion, treatment failure and embolisms can be prevented]. Lakartidningen. 2015 Nov 10;112:DMP6. Swedish. PMID: 26556450.

Webster J, Osborne S, Rickard CM, Marsh N. Clinically‐indicated replacement versus routine replacement of peripheral venous catheters. Cochrane Database of Systematic Reviews 2019, Issue 1. Art. No.: CD007798. DOI: 10.1002/14651858.CD007798.pub5.

Published

2023-05-07

How to Cite

Araujo, J., Billordo, B., Alvarez, C., Osardo, V., & Di Líbero, E. (2023). Pharmaceutical intervention on peripheral vascular access in a general acute hospital. Revista De La AAFH, 9(2), 9–19. Retrieved from https://revista.aafhospitalaria.org.ar/index.php/RAAFH/article/view/41

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